| Author | Article with link to Abstract | Need to Know Article with link to PDF |
|---|---|---|
| Peter M. Reardon, MD*; Christian Vaillancourt, MD, MSc* | Kent AP, Brueckmann M, Fraessdorf M, et al. Concomitant oral anticoagulant and nonsteroidal anti-inflammatory drug therapy in patients with atrial fibrillation. J Am Coll Cardiol 2018;72 (3):255–67. | Adverse events associated with nonsteroidal anti-inflammatory drug use among patients taking oral anticoagulants |
| Jarrett Moore, BSc*; Mark Sanderson, BSc, MD†; Riyad B. Abu-Laban, MD, MHSc‡ | Perkins GD, Ji C, Deakin CD, et al. A randomized trial of epinephrine in out-of-hospital cardiac arrest. N Engl J Med 2018; epub, NEJMoa1806842. | Epinephrine in cardiac arrest: The PARAMEDIC2 trial |
| Mathieu Brunet, MD*; Tim Chaplin, MD* | Atkinson PR, Milne J, Diegelmann L, et al. Does point-of-care ultrasonography improve clinical outcomes in emergency department patients with undifferentiated hypotension? An international randomized controlled trial from the SHoC-ED Investigators. Ann Emerg Med 2018;72 (4):478–89. | Does point-of-care ultrasonography improve clinical outcomes in emergency department patients with undifferentiated hypotension? |
| Ian Surdhar, MD, MSc*; Anne Finlayson, MD*; Tomislav Jelic, MD* | Gaspari RJ, Sanseverino A, Gleeson T. Abscess incision and drainage with or without ultrasonography: a randomized controlled trial. Ann Emerg Med 2019;73:1–7. | Does point-of-care ultrasonography (POCUS) reduce clinical failure rates in patients undergoing incision and drainage for an uncomplicated abscess? |
| James Ahlin, MD*; Melanie Walker, PhD*; David Messenger, MD, MM* | Gottlieb M, DeMott JM, Hallock M, Peksa GD. Systemic antibiotics for the treatment of skin and soft tissue abscesses: a systematic review and meta-analysis. Ann Emerg Med 2019;73(1):8–16. | Do systemic antibiotics for skin and soft tissue abscesses after incision and drainage improve cure rates compared with placebo? A critical appraisal |
| Nicholas Packer, MD, MSc*; Miles Hunter, MD*; Shawn Dowling, MD* | Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK, et al. Clinical trial of fluid infusion rates for pediatric diabetic ketoacidosis. N Engl J Med 2018;378(24):2275–87. | Does the tonicity or rate of intravenous fluid infusion affect neurologic outcomes in children with diabetic ketoacidosis? |
| Geordon Avery-Cooper, MD*; Scott Seadon, MD* | Casey JD, et al. Bag-mask ventilation during tracheal intubation of critically ill adults. N Engl J Med 2019;380(9):811–21. | Does bag-mask ventilation between induction and laryngoscopy reduce the incidence of hypoxemia during intubation of critically ill patients? |
| Margaret Hull, MDCM* | Trial: Johnston SC, Easton JD, Farrant M, et al. Clopidogrel and aspirin in acute ischemic stroke and high-risk TIA. N Engl JMed 2018;379(3):215-25. Protocol: Johnston SC, Easton JD, Farrant M, et al. Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. Int J Stroke 2013;8(6):479-83. | Dual antiplatelet treatment in TIA and high-risk ischemic CVA, a review of the POINT trial |
| Miles Hunter, MD*; Nicholas Packer, MD, MSc*; Shawn Dowling , MD* | Osmond M, Klassen T and Wells G. Validation and refinement of a clinical decision rule for the use of computed tomography in children with minor head injury in the emergency department. CMAJ 2018;190:E816–22 | Does the CATCH clinical decision rule adequately determine which children with minor head injury require computed tomography (CT) imaging? |
| Brett H. Shaw , MD, MSc*; Marshall Ross, MD* | G. Andolfatto, K. Innes, W. Dick, S. Jenneson, E. Willman, R. Stenstrom, P.J. Zed, G, Benoit. Prehospital analgesia with intranasal ketamine (PAIN-K): a randomized double-blind trial in adults. Ann Emerg Med 2019;74(2):241–50. | Is Intranasal Ketamine Safe and Effective as a Prehospital Analgesic? |
| Andrew Guy , MD*; Riley Golby, MD*; Rob Stenstrom, MD, PhD* | Lemkes JS, Janssens GN, van der Hoeven NW, et al. Coronary angiography after cardiac arrest without ST-segment elevation. N Engl J Med 2019;380(15):1397–407. | Coronary angiography after cardiac arrest without ST-segment elevation (COACT) |
| Riley Golby, MD*; Andrew Guy , MD*; Frank X. Scheuermeyer, MD, MHSc* | Pellatt R, et al. Is buddy taping as effective as plaster immobilization for adults with an uncomplicated neck of fifth metacarpal fracture? A randomized controlled trial. Ann Emerg Med 2019;74(1):88–97. | Is buddy taping as effective as plaster immobilization to manage adult boxer's fractures? |
| Ariel Hendin, MD*; Matthew Lipinski, MD* | Ma H, Campbell BCV, Parsons MW, et al. Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. N Engl J Med 2019;380(19):1795–803. | Extending the window for thrombolysis in acute ischemic stroke? |
| Tyson Savage, MD*; Zoe Polsky, MD*; Marshall Ross, MD FRCPC(EM)* | Karlow N, Schlaepfer CH, Stoll CR, Doering M, Carpenter CR, Colditz GA, Motov S, Miller J, Schwarz ES. A systematic review and meta-analysis of ketamine as an alternative to opioids for acute pain in the emergency department. Acad Emerg Med 2018;25(10):1087–97. | Is low-dose ketamine an effective and safe alternative to opioids for treatment of acute pain in the emergency department? |
| Geneviève Gravel, MD*; Alain Miclette, MD, MBA*; Roxane Beaumont-Boileau, MD*; Julie Côté- Leclerc, MD*; Marcel Émond , MD, MSc*†‡§ | Twerenbold R, Costabel JP, Nestleberger T, et al. Outcome of applying the ESC 0/1-hour algorithm in patients with suspected myocardial infarction. J Am Coll Cardiol 2019;74(4):483–94. | Outcome of applying the European Society of Cardiology (ESC) 0/1-hour algorithm in patients with suspected myocardial infarction |